7-Fluoro-3-(methoxymethoxy)-8-[(triisopropylsilyl)ethynyl]naphthalene-1-boronic Acid Pinacol Ester
1,3,2-Dioxaborolane, 2-[7-fluoro-3-(methoxymethoxy)-8-[2-[tris(1-methylethyl)silyl]ethynyl]-1-naphthalenyl]-4,4,5,5-tetramethyl-
CAS: 2621932-37-2
Molecular Formula: C29H42BFO4Si
7-Fluoro-3-(methoxymethoxy)-8-[(triisopropylsilyl)ethynyl]naphthalene-1-boronic Acid Pinacol Ester - Names and Identifiers
7-Fluoro-3-(methoxymethoxy)-8-[(triisopropylsilyl)ethynyl]naphthalene-1-boronic Acid Pinacol Ester - Physico-chemical Properties
| Molecular Formula | C29H42BFO4Si |
| Molar Mass | 512.54 |
7-Fluoro-3-(methoxymethoxy)-8-[(triisopropylsilyl)ethynyl]naphthalene-1-boronic Acid Pinacol Ester - Introduction
2-(7-Fluoro-3-(methoxymethoxy)-8-(2-triisopropylsilynyl)-1-naphthyl)-4,4,5,5-Tetramethyl -1,3, 2-dioxabororane (also known as 1,3, 2-dioxaborolane, or simply 1,3, 2-dioxabororane), the chemical properties of which depend mainly on its structure.
The chemical properties of this compound include:
-Molecular formula: C30H39BF3O3Si
-Molecular weight: 536.55g/mol
-Appearance: White Crystal
-Melting Point: 140-150 ° C
-Boiling point: 350-360 ° C
-Solubility: Good solubility in common organic solvents
This compound is commonly used in boronation reactions in organic synthesis, especially for the synthesis of organic aromatic hydrocarbons and organic synthetic compounds. Other applications also include:
-Use as a fluorescent dye or probe
-Participate in the synthesis of derivatives of optical and electronic materials
-Participate in the design and synthesis of catalysts as ligands
The preparation method of 1,3, 2-dioxabororane is mainly obtained by chemical synthesis. The following is a common preparation method:
1. First, 7-fluoro-3-(methoxymethoxy)-8-(2-triisopropylsilynyl) -1-naphthyl-4, 4,5,5-tetramethyl -1,3, 2-dioxabororane reacts with a condensing agent (such as N,N-dimethylformamide) to generate 1,3, intermediates of 2-dioxabororane.
2. Next, the intermediate is reacted with a Boronic ester to generate the target product 1,3, 2-dioxabororane.
Regarding the safety information of this compound, the following are some common safety precautions:
-This compound may have an irritating effect on the eyes and skin. During handling, direct contact should be avoided.
-Operate in a well-ventilated place and use appropriate personal protective equipment, such as gloves and protective glasses.
-Avoid inhaling dust or vapors. If inhaled into the respiratory tract, should be quickly moved to fresh air.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
The chemical properties of this compound include:
-Molecular formula: C30H39BF3O3Si
-Molecular weight: 536.55g/mol
-Appearance: White Crystal
-Melting Point: 140-150 ° C
-Boiling point: 350-360 ° C
-Solubility: Good solubility in common organic solvents
This compound is commonly used in boronation reactions in organic synthesis, especially for the synthesis of organic aromatic hydrocarbons and organic synthetic compounds. Other applications also include:
-Use as a fluorescent dye or probe
-Participate in the synthesis of derivatives of optical and electronic materials
-Participate in the design and synthesis of catalysts as ligands
The preparation method of 1,3, 2-dioxabororane is mainly obtained by chemical synthesis. The following is a common preparation method:
1. First, 7-fluoro-3-(methoxymethoxy)-8-(2-triisopropylsilynyl) -1-naphthyl-4, 4,5,5-tetramethyl -1,3, 2-dioxabororane reacts with a condensing agent (such as N,N-dimethylformamide) to generate 1,3, intermediates of 2-dioxabororane.
2. Next, the intermediate is reacted with a Boronic ester to generate the target product 1,3, 2-dioxabororane.
Regarding the safety information of this compound, the following are some common safety precautions:
-This compound may have an irritating effect on the eyes and skin. During handling, direct contact should be avoided.
-Operate in a well-ventilated place and use appropriate personal protective equipment, such as gloves and protective glasses.
-Avoid inhaling dust or vapors. If inhaled into the respiratory tract, should be quickly moved to fresh air.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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CAS: 2621932-37-2
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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